There are potentially many different causes of male infertility, including hormonal, anatomical, and secondary to exposure to exogenous substances. In many cases of MFI, a definitive cause for abnormalities is never identified.
Assessment of sperm DNA damage has been suggested as a negative predictor of fertility potential. Multiple pathological factors acting at both the intra-testicular and post-testicular levels may contribute to sperm DNA damage.
Visit for more related articles at Journal of Fertilization: Semen samples of patients were analyzed using computer-assisted semen analysis CASA.
In recent years, with the advancement in sperm cell biology and the development of additional testing techniques, sperm DNA fragmentation has been recognized as one of the important causes of reduced fertility potential. Elevated sperm DNA fragmentation rates also significantly diminish the chance of success in assisted pregnancies.
Due to this, Fertility Solutions performs a conventional semen analysis for all male patients. We evaluate seminal volume, pH, sperm concentration, motility, morphology and antibodies.
New research from Queen's University Belfast has uncovered the cause of infertility for 80 per cent of couples previously diagnosed with 'unexplained infertility'. At present some 50, couples require fertility treatment across the UK each year, with the figure reaching one million worldwide.
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